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Wednesday Mar 14 2001 | Updated 0057 hrs IST 1427 EST
Glaxo brings Zyban to smoke out addiction

Gauri Kamath
MUMBAI
GLAXO India is setting great store by Zyban, a pill to help quit smoking which will hit the shelves in May. The company is gearing up for a high-profile launch of the drug backed by a social campaign against smoking.

For the drug major, Zyban comes at a time when it has had a lacklustre financial performance with not many product launches to prop up the bottomline.

Zyban, which is in the top 10 list of new products for parent firm GlaxoSmithKline in 2000, is seen by Glaxo to be a potential "blockbuster" in India which has about 37 million smokers.

Though Glaxo officials maintain that the India price has not yet been fixed, they claim it would work out cheaper on a daily basis than smoking a pack of cigarettes.

"It would also depend on the customs duty (the drug is being imported)," said Kal Sundaram, director, pharmaceuticals, Glaxo India. The company may approach the government to waive the duty under the exemption list for lifesaving drugs.

"This is a lifestyle product and will have to be marketed as one. Glaxo could have the first mover advantage in the local market, but it has to get the pricing right. In the past, companies like Cipla have given it a run for its money because of cheaper pricing," said Shahina Mukadam, analyst at Development Bank of Singapore.

In Singapore, the drug is priced at the equivalent of Rs 6000 for the entire sevenweek regimen. Mukadam said, in India, it may have to be half that price.

The nicotine-free drug, Zyban works by preventing a fall in the levels of neurotransmitters dopamine and noradrenaline in the body. It is the fall in these levels which result in withdrawal symptoms when a smoker stops smoking.

Clinical trials and case studies have shown that quitters do not experience these symptoms if they stop smoking while on Zyban which improves the success rate, said S M Chandrashekhar, medical advisor, Glaxo India.

Currently, the other forms of treatment available to smokers include nicotine replacement therapy i.e. releasing safe levels of nicotine into the blood stream through media like gums and patches.

Swiss multinational Novartis India has been marketing NRT patches under the brand name Nicotinnell. This is but not a major product for the firm.
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